Tag Archives: drugs

Marketed Drugs Have No Value

MDC says, The Most Marketed Drugs Have The Least Therapeutic Value !!!

The pharmaceutical industry spends a lot of money on getting doctors and patients to buy their products. Americans are probably most familiar with those TV and radio commercials that end with the long list of side effects narrated in super-speed, but may not realize that their doctors are getting their own special brand of marketing, too. If that sounds suspect, it should. Two studies from the U.S. and Canada show that the drugs that pharma companies spend the most time promoting to doctors have the leasttherapeutic value.

All The Better To Sell You With, My Dear

Here’s something that might feel a little weird: your doctor has probably gone to lunch with a pharmaceutical industry representative, and the rep probably picked up the check. Some hospitals and medical programs forbid the practice, but for those that don’t, doctors routinely receive free meals, drinks, and small gifts from pharma reps hoping to increase their sales. Companies in the U.S. are required to report every payment to doctors of $10 or more. According to Open Payments, the online database of those reports, pharmaceutical companies spent $8.2 billion in 2016 promoting drugs to more than half a million physicians. (You can use the tool yourselfto see what your own doctor has been paid.)

And this kind of promotion works. Studies show that doctors who are allowed to accept these gifts are more likely to prescribe brand-name drugs, even when cheaper generics are available. That’s why two studies, an American one published in the British Medical Journal in May 2017 and a Canadian one published in the Canadian Medical Association Journal in September 2017, are so troubling. They found that the most-promoted drugs were the least likely to be therapeutically valuable — or, as the BMJ study defined it, “effective, safe, affordable, novel, and represent a genuine advance in treating a disease.”

What kinds of drugs are we talking? In the U.S., the top three most heavily promoted drugs were Eliquis, an anticoagulant that can reduce stroke risk in some patients, and Bydureon and Invokana, two drugs for type II diabetes that are formulated to lower blood sugar. Invokana was also among Canada’s most promoted drugs, along with the blood-pressure drug Coversyl and the asthma/COPD medication Breo Ellipta. All of them were rated as having little therapeutic value, and not representing anything new in the pharmaceutical market.

The Greater Good

Of course, this does make sense. A revolutionary, must-have drug sells itself. “If a genuinely innovative drug becomes available that significantly advances patient care … this information might be expected to spread rapidly among clinicians,” the authors of the BMJ study write. “Conversely, a ‘me-too’ drug with minimal benefit over previous treatments in a class with generic alternatives … might need robust promotion to facilitate its use.”

This doesn’t suggest that the relationship between doctors and pharmaceutical reps is a sign of corruption. After all, many drugs are useful, and doctors don’t necessarily have time to constantly research every new drug out there. As a 2017 editorial in the Journal of the American Medical Association pointed out, “In the United States, there is no formal approach to educating physicians about new drugs. In the absence of such a system, physicians must either find information about new therapies from other sources, such as by reading or attending meetings, or accept information from pharmaceutical representatives.”

It does mean, however, that patients should be vigilant and educated about their own care. Research what pharmaceutical companies your doctor and doctor’s office have had contact with. When your doctor prescribes a drug, ask if there are effective generic alternatives. The more information you have, the better off you’ll be.

source: curiosity

Quaaludes and Bill Cosby

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What is this connection to Bill Cosby and Quaaludes?

Until the revelations of Bill Cosby’s past sexual behaviors no one spoke of quaaludes, and that drug needs to be explained in it’s time frame connecting to the history of the Viet Nam War.

Before the United States Government pulled Quaaludes off the available market somewhere in the late seventies, they were known by many names, Ludes, Sopers, 714’s, just a few.

The angry war torn sixties bred riots in Los Angeles, Detroit, and many Cities across America, and cities were ready to go into flames after the deaths of MLK, and RFK. America’s youth were just about out of control.. All Americans were split between supporting patriotically or resisting patriotically the Viet Nam War.

Out of the blue one day in those late sixties, a muscle relaxant hit the streets. A new heart medicine, and this pill had an unexpected side effect, it removed any sexual inhibitions. Inhibitions fell away and an angry generation turned into a love mush. We made love not war and that was a way to cope with the insanity of it all.

The high from ingesting a Lude, is as if you were drinking all night without having the side effects of a hangover.

“Looking for Mr. Goodbar”, a film portraying a life taken over by quaaludes, was the only film exploring the affects of the soporific high and gave an accurate portrait of how one felt during and after. It is a very good movie.

The Love Drug by any other name never swept a new generation like the “quaalude”. You can have your blue pill, Viagra, or it’s equivalent, what the blue pill lacks is the extraordinary ability of a Lude to remove one’s inhibitions. Inhibitions disappeared, Can you imagine a tightly strung individual, who tried uppers and downers, who has smoked all varieties of hash and pot, and is still trying to cope with the Draft, the Politics, all that the Viet Nam periods generation endured, and comes across a pill that wants you to love the one your with, take your clothes off, enjoy your body and let worries fade away. What! You don’t get a hangover? Not unless you have four or five Ludes at a time.

Those were uptight times. The boomer generation and the small part of the preceding generations dreams and aspirations were thrown away with the death of JFK. That cover-up known as the Viet Nam War, hiding the atrocities created in conceiving the assassinations of the leaders of real change with more war and fear of Commie threats has ruined truth maybe permanently.

Quaaludes were a fix, albeit a way to calm the young among us. I am sure that if they were available today they would be as popular as ever. The side affects of Quaaludes were the breaking down of the immune system, Viral infections were common.

None the less having a Lude was good medicine and the boomers who enjoyed that moment of love have never lost the gift losing inhibitions brought, almost like what love in Paradise would be like. It was hard to come down from that.

With that historic small perspective you can now understand that two generations ago, when Timothy Leary rode that Magic Bus across America dropping LSD in little towns and villages, cities and countryside, when he spoke of that time he said most brilliantly, “How did I know not everyone wanted to fly”.

When we look back today, at yesterday, and how we played to cope with the insanity of Viet Nam by doing pills and drugs, we listened to the artists and they were doing the same drugs to cope. In the burbs the housewives were on pills, and today it seems everyone is on some pill or another.

If America comes off of the multiple highs each of us instantly gratify each day, then maybe we can forgive an old comedian who everyone hit on, well he is human after all, and he ain’t the first celeb Player fawned over, just the most recent society hungers to knock off their pedestal, the one we created.

The Placebo Effect

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Expensive drugs work better than cheap ones — or at least some people firmly believe they do.

Researchers told 12 patients with Parkinson’s disease that they were testing two drugs, one costing $100 and one $1,500 per dose. The drugs contained the same dose of the same medicine, they explained, but the manufacturing processes were different, and they wanted to see if they worked equally well. The study was published by the journal Neurology.

What the subjects did not know is that they all received an identical injection of a plain saline solution.

The “expensive” placebo worked significantly better, producing a two-fold improvement compared with the “cheap” one. The effect was apparent not only in tests of physical ability, but also as measured by brain imaging. In fact, the effect of the expensive placebo was not significantly different from that of levodopa, the most effective medication for Parkinson’s disease.

Levodopa acts by raising levels of the neurotransmitter dopamine in the brain.

“One of the reasons why the effect is so large is that it’s mediated by dopamine,” said the lead author, Dr. Alberto J. Espay, an associate professor of neurology at the University of Cincinnati. “We make more dopamine when we have heightened expectations of efficacy.”

When the subjects were told the true nature of the study, the researchers write, the reactions ranged from incredulity to astonishment.

Source: By NICHOLAS BAKALAR

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Opium For Sale

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America’s war on drugs is failing in Afghanistan, with opium production at record levels, despite spending $7.5 billion to tackle the problem. Over 200 thousand hectares is used to grow opium, an increase of 36 percent, according to a US report.

MDC says , how else will the United States fund their wars.

The report, which was commissioned by SIGAR, the Special Inspector General for Afghanistan Reconstruction makes grim reading, with opium poppy cultivation increasing by over a third, while the country now has about 1.3 million heroin users. This is a ten-fold increase compared to 2005, when around 130,000 people were using the drug.

Afghanistan is responsible for about three-quarters of the world’s heroin production, with much of it being cultivated in the Helmand and Kandahar provinces in the south of the country. However, the US has concentrated most of its efforts in the east of Afghanistan, which has relatively little poppy production, as it is safer than working in the south.

Attempts to limit production and seize heroin have not been helped due to a downscaling of operations by the ISAF (International Security Assistance Force). In 2013, coalition forces managed to seize 41,000 kilograms of opium out of the 5.5 million kilograms produced in Afghanistan.

“Drug labs, storage sites, and major trafficking networks are concentrated in rural areas that are increasingly off-limits to Afghan forces due the ISAF drawdown and declining security in these areas,” the report found.

Since NATO began its ‘War on Terror’ in 2001, heroin production in Afghanistan has increased 40-fold, according to the head of Russia’s Federal Drug Control Service. “Afghan heroin has killed more than 1 million people worldwide since ‘Operation Enduring Freedom’ began, and over $1 trillion has been invested in transnational organized crime from drug sales,” Viktor Ivanov said earlier at a conference on the Afghan drug problem in 2013.

Moscow has repeatedly pushed for the eradication of poppy fields in Afghanistan as the simplest solution. NATO, however, seems to have no intention of doing so.

In 2013, the Afghan Ministry of Counter Narcotics reported that just 7,300 hectares of poppy fields had been destroyed, which was only three percent of the total opium fields in the country. The US has spent $7.5 billion since 2002 trying to combat the problem of opium production. However, despite these vast sums very little impact has been made on the amount of heroin appearing on the world market.

Source.: rt

The Poppy

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MDC issues a congratulations to the United States military. You are the largest drug dealer.

Afghanistan’s opium production surged to record levels this year, the UN says.

The harvest this May resulted in 5,500 metric tons of opium, 49% higher than last year and more than the combined output of the rest of the world. Even Afghan provinces with some past successes in combating poppy cultivation saw those trends reversed, according to this year’s annual UN Office on Drugs and Crime (UNODC) report.

The withdrawal of foreign troops next year is likely to make matters worse, said Jean-Luc Lemahieu, the UNODC regional representative in Kabul. He warned that as international assistance falls off, the Afghan government will become increasingly reliant on illicit sources of income.

Uncertainty is also driving up poppy production, as farmers worried about the country’s future turn to the tried and tested.

The big increase in production began in 2010 when farmers rushed to plant to take advantage of soaring prices, a result of a crop disease the previous year, the US military surge in the south and the announcement of the US and Nato’s transition out of Afghanistan, Mr Lemahieu said.

He added that those who benefit from the drug trade include farmers, insurgents and many within the government. Often, he said, they work together.

Khan Bacha, who cultivates a small plot of land in eastern Nangarhar province, a Taliban stronghold, said this week that the insurgents charge farmers a “religious tax” of one kilo of opium for every 10 kilos produced – though the price is “negotiable”.

“They say we are going for jihad,” Mr Bacha said. “It is the god money we give.”

Past attempts by the international community to combat opium cultivation have included introducing alternative crops and paying farmers in some areas not to plant poppies. That backfired when farmers elsewhere started growing poppies in the hopes of getting money if they stopped.

Cultivation also appears to be spreading to new parts of the country – with Afghans planting poppies in 516,450 acres across 17 provinces this year, compared with 380,540 acres in 15 provinces last year, according to the report.

The vast majority of Afghanistan’s poppy cultivation takes place in the south, south west and east, areas where the Taliban insurgency is thriving. But Kabul province in central Afghanistan saw a major spike, with a 148% increase in cultivation between 2012 and 2013.

But it wasn’t all bad news in the report, which said Afghanistan has expanded its social services to deal with a growing addiction problem at home.

FDA Fast-Track

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(NaturalNews) The U.S. Food and Drug Administration (FDA) wants to expand the list of drug types eligible for its so-called “Fast Track, Accelerated Approval and Priority Review” process, which is really just a fraudulent shortcut method for drug companies to rush potentially-deadly new drugs to market without appropriate regulatory review. According to reports, the FDA plans to allow certain obesity treatments, antibiotics, and other drugs to be peddled to the masses without first undergoing the normal drug review process, a scheme the agency claims is in the best interests of public health.
The changes, which FDA Commissioner Margaret Hamburg recently proposed to a group of scientific advisers, would fast-track certain untested drugs to market via condensed clinical trials, would have smaller sample sizes and entail shorter duration periods. These same fast-tracked drugs would also receive a special type of priority approval status, allowing them to be prescribed by doctors to so-called “critical need” patients willing to bear the drugs’ unknown side effects.

“Under the new pathway, the FDA would allow developers of such drugs to conduct smaller, faster clinical trials, and provide a ‘special medical use’ label which would allow doctors to administer drugs to patients with critical need,” says MedCity News about the proposed new FDA protocols. “(Commissioner) Hamburg has said that the FDA needs to take into account the needs people with deadly or debilitating diseases that may be willing to take on the risks of unproven drugs.”

So while the FDA strongly opposes the use of natural supplements to treat conditions like obesity and chronic infections because they have never undergone the official FDA approval process and are thus “unproven,” the agency wants to give untested, unproven drugs an arbitrary stamp of approval, even though these synthetic substances could end up killing patients. Such blatant hypocrisy illustrates how utterly corrupt the FDA has become with its patently obvious bias towards pharmaceutical drugs.

The FDA has already been fast-tracking untested and unproven cancer drugs to market with the unenforced stipulation that drug companies perform post-market approval studies to verify safety and effectiveness. But in most cases, the companies responsible for such drugs never perform any follow-up studies, and the FDA imposes no penalties or restrictions on them for violating the law. Many new drugs, in other words, are being administered to patients without ever having been at all evaluated for safety or effectiveness.

OverMedicated

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Nearly 70 percent of Americans take at least one prescription drug and more than 50 percent take two, scholars writing in Mayo Clinic Proceedings say. Antibiotics, antidepressants and painkilling opioids are most commonly prescribed, they found. 20 percent of patients are on five or more prescription medications, according to the findings.

MDC says, try and avoid the doctor and utilize natural remedies. Doctors are the drug dealer!

17 percent of those studied were prescribed antibiotics, 13 percent were taking antidepressants and 13 percent were on opioids. Drugs to lower lipids, such as cholesterol, came in fourth (11 percent) and vaccines were fifth (11 percent). Drugs were prescribed to both men and women across all age groups, except high blood pressure drugs, which were seldom used before age 30.

Overall, women and older adults receive more prescriptions. Vaccines, antibiotics and anti-asthma drugs are most commonly prescribed in people younger than 19. Antidepressants and opioids are most common among young and middle-aged adults. Cardiovascular drugs are most commonly prescribed in older adults.

Women receive more prescriptions than men across several drug groups, especially antidepressants: Nearly 25 percent of women ages 50-64 are on an antidepressant.
The statistics from the Rochester Epidemiology Project in Olmsted County, Minn. are comparable to those elsewhere in the United States, says study author Jennifer St. Sauver, Ph.D., a member of the Mayo Clinic Population Health Program in the Mayo Clinic Center for the Science of Health Care Delivery.

“Often when people talk about health conditions they’re talking about chronic conditions such as heart disease or diabetes,” St. Sauver says. “However, the second most common prescription was for antidepressants — that suggests mental health is a huge issue and is something we should focus on. And the third most common drugs were opioids, which is a bit concerning considering their addicting nature.”

For several drug groups, use increases with advancing age.

“As you get older you tend to get more prescriptions, and women tend to get more prescriptions than men,” St. Sauver says.

Prescription drug use has increased steadily in the U.S. for the past decade. The percentage of people who took at least one prescription drug in the past month increased from 44 percent in 1999-2000 to 48 percent in 2007-08. Spending on prescription drugs reached $250 billion in 2009 the year studied, and accounted for 12 percent of total personal health care expenditures.

Drug-related spending is expected to continue to grow in the coming years, the researchers say.

MDC says again, doctors are the drug dealers and Americans are OverMedicated!

Ecstasy Works

FDA approves first study on ecstasy-assisted therapy for social anxiety in autistic adults (via Raw Story )

The U.S. Federal Drug Administration in late April approved a study to examine whether the drug ecstasy could help autistic adults suffering from social anxiety. But the first-of-its-kind study still has some hurdles to jump over before it can begin. “The study could start enrolling subjects in several…

Continue reading Ecstasy Works

Ditch the Prescription

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Americans who ditch overpriced prescriptions save time, money, and health.

Many Americans are now looking outside the United States for cheaper prescription drugs. The pharmaceutical industry estimates the cost of developing a new drug is at least 800 million dollars. This helps explain the high price that is passed on to consumers, but does medicine have to be this expensive? According to the National Consumers League, consumers are paying too much for prescription medication. This has led many to cross the border and start buying their prescriptions at half the price in places like Canada.

Alison Rein of the National Consumers League, says, “The fact that busloads of Americans are crossing the border buying medications or going online is a clear sign that the public finds the price of prescription drugs is too high in the United States.”

People are fed up with overrated, high priced prescriptions!

According to the Centers for Disease Control (CDC), the United States out-of-pocket drug consumption exceeds $45 billion annually. The agency also reports that one of every five Americans ask their doctor for a less expensive prescription.

The horrible reality is: the 11 major drug companies in the world come up with an annual $85 billion profit. This industry is obviously monopolizing on people’s illness, and they’re not even sharing any of the billion-dollar profit by lowering the prices!

Either way, the combination of severe side effects and high costs is detracting people from the pharmaceutical philosophy altogether. Many people are now seeking alternative answers as well.

If prescriptions are too expensive, why not try prescribing your own medicine?

As Americans look for more frugal answers to their health, the truth may be just under their nose. As awareness spreads, many are learning how to make their own medicine. Real medicine might not be in the doctor’s hands anymore. Many medical doctors are beginning to encourage their patients to seek nutritional answers. Many doctors confess that they wouldn’t consume the very drugs they prescribe to people. Maybe prescriptions are really just bogus disease management tools designed to keep people coming back to an overly priced, overrated juggernaut.

There are answers outside the industry. Real medicine might actually be just outside the doctor’s office building, growing in the nearby field. Naturally existing plants like red clover or barks from the white willow tree are cheaper, more effective medicines for those who utilize them.

Red Clover – an abundant, freely growing food medicine.

Red clover is an abundant growing blossom found growing in fields, yards, parks, and ditches. It contains many valuable nutrients including calcium, chromium, magnesium, niacin, phosphorus, potassium, thiamine, and vitamin C. Brewed as a tea or eaten in salad, red clover is an essential food medicine that is a rich source of isoflavones. Studies show that isoflavones help with hot flashes, breast enhancement, lowering cholesterol, improving urine production and circulation of the blood. When used in women, red clover prevents osteoporosis. In men, it limits the development of benign prostate hyperplasia.

Peel off some bark from the white willow tree to relieve your pain. A certain Woodstock hippie informed us of the magic, willow water and the benefits.

Just beyond the red clover field, one might find a beautiful drooping white willow tree. A trunk full of pain relief, the bark of the white willow tree has a long history of use. According to the University of Maryland Medical Center, white willow is used to help with osteoarthritis, lower back pain, and headaches. Its main ingredient, salicin, acts much like aspirin. In fact, in the 1800s, salicin aided in creating aspirin. Salicin doesn’t work as fast as modern aspirin but its effects last longer. White willow is virtually free to obtain as well and doesn’t damage the liver like pharmaceutical pain killers. When the bark is steeped in glycerin, vinegar, or alcohol for up to a month, the salicin is extracted into the liquid medium and preserved, creating a homemade remedy. When the bark is strained out of the mixture, the resulting liquid medium can now be used under the tongue or in a glass of water as a safe pain relief.

There are cheap, easy ways to stay healthy and live strong, without prescriptions. Prescriptions are draining the pocket book of countless Americans and breaking down their health along the way. Natural options will grow in popularity as people turn away from the overrated, overpriced system of pharmaceutical drugs.

Source: naturalnews

Z-Pack Warning

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MDC asks, why not try homeopathic remedies and herbs? Get away from the doctor and the system .

Check your medicine cabinet. You might have a common drug which a new FDA warning says may carry serious or even fatal heart risks.

The warning comes 10 months after a study published in the New England Journal of Medicine found a small increase in cardiovascular deaths among people being treated with azithromycin, usually called Z-Pak capsules.

The capsules are a good, broad spectrum antibiotic taken over five days to fight respiratory infections.

But now the FDA says people with certain heart problems are at a higher risk of having serious side-effects from azithromycin, which the FDA warning says “can cause abnormal changes in the electrical activity of the heart that may lead to a potentially fatal irregular heart rhythm.”
Doctors and pharmacists are taking note.

“The warning is meant for prescribers just to alert them that there is this incidence of increased risk of cardiac death for people that took Z-Pak that already had this heart defect,” said Andy Komuves with Dougherty’s pharmacy in Dallas.

“The warning specifically deals with the patient group of people that have heart defects that cause arrhythmia, people who have something called prolonged QT interval, which is a type of arrhythmia and people who have slow heart rate or people who are potassium or magnesium deficient,” said Komuves. “If you’re not one of those patients, you don’t have to worry about the Z-Pak.”

Source: http://www.nbcdfw.com

Good Poppy BAD Poppy

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UPDATE TO PAST BLOG, “WE CALLED IT.” Thank you RT News & Wiki.
Afghanistan has been the greatest illicit opium producer in the entire world, ahead of Burma (Myanmar), the “Golden Triangle“, and Latin America since 1992, excluding the year 2001.[1] Afghanistan is the main producer of opium in the “Golden Crescent“. Opium production in Afghanistan has been on the rise since U.S. occupation started in 2001. Based on UNODC data, there has been more opium poppy cultivation in each of the past four growing seasons (2004–2007) than in any one year during Taliban rule. Also, more land is now used for opium in Afghanistan than for coca cultivation in Latin America

MDC has a COMPLAINT!!!

 

I would rather have the government buy the POPPIES from Afghanistan, than eradicate them.

Poppies are used in medicine, and in our country, the pharmaceutical companies distribute the bi-products of poppies and are licensed by the government to control their use.  Other countries, and governments, set up their own forms of controls when utilizing the medicinal benefits these products deliver.

Poppies are grown in many countries, are harvested, and their by-products get distributed throughout the world, and drug companies create the products our doctors and hospitals use in the practice of medicine.

In Afghanistan, the poppy has been used and grown through millennia.  Somewhere in the last century the drugs derived from the poppy have found, that governments want to control the use rather than allow the public to have and use these products at their own risk.  The Afghanistan poppy found a large clientele in Europe and the West, via the distribution of heroin.  When Russia invaded Afghanistan in the 1980’s, the soldiers from the invading army became widely addicted to heroin and their habits were brought back to dear Mother Russia as a gift from the Afghanis’.

In Thailand and the Golden Triangle, the poppy is grown legally and is a major product exported and controlled.  Their is the possibility that the parties who control the distribution of these fields of poppies would not appreciate the competition offered by the Afghanistan poppy or poppies grown anywhere else in the world.

The creation of so many criminal laws over the poppy or opiates, have filled the prisons in the United States to overflowing.  We cannot afford these prisons and the corporations that want to maintain them.  If corporations are behind the drug laws imposed on our society, even with the horrible results drugs do by destroying families and lives, then that is a corporate agenda.

 

The Drug War was lost a long time ago.  Today a recent study found that Alzheimer sufferers when given painkillers had better results than the Alzheimer drugs formulated by the drug companies.  Alzheimer victims were suffering in most cases from pain.

Until the sources who push our society towards creating laws that create criminals are reasoned with, to show that they are imposing costs to society that affect them and the children they create, that they have a stake in doing things without doing harm to person or planet, then I shall have to suffer and you shall have to listen to my complaint.